Design, synthesis, and antiprotozoal evaluation of new 2,4-bis[(substituted-aminomethyl)phenyl]quinoline, 1,3-bis[(substituted-aminomethyl)phenyl]isoquinoline and 2,4-bis[(substituted-aminomethyl)phenyl]quinazoline derivatives

• Main Authors: Jean Guillon (Author), Anita Cohen (Author), Clotilde Boudot (Author), Alessandra Valle (Author), Vittoria Milano (Author), Rabindra Nath Das (Author), Aurore Guédin (Author), Stéphane Moreau (Author), Luisa Ronga (Author), Solène Savrimoutou (Author), Maxime Demourgues (Author), Elodie Reviriego (Author), Sandra Rubio (Author), Sandie Ferriez (Author), Patrice Agnamey (Author), Cécile Pauc (Author), Serge Moukha (Author), Pascale Dozolme (Author), Sophie Da Nascimento (Author), Pierre Laumaillé (Author), Anne Bouchut (Author), Nadine Azas (Author), Jean-Louis Mergny (Author), Catherine Mullié (Author), Pascal Sonnet (Author), Bertrand Courtioux (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A series of new 2,4-bis[(substituted-aminomethyl)phenyl]quinoline, 1,3-bis[(substituted-aminomethyl)phenyl]isoquinoline, and 2,4-bis[(substituted-aminomethyl)phenyl]quinazoline derivatives was designed, synthesised, and evaluated in vitro against three protozoan parasites (Plasmodium falciparum, Lei...