The effect of allopurinol on renal outcomes in patients with diabetic kidney disease: A systematic review and meta-analysis

• Main Authors: Binbin Wu (Author), Lili Chen (Author), Yuankai Xu (Author), Qingqing Duan (Author), Zhibo Zheng (Author), Zhigui Zheng (Author), Dongyuan He (Author)
• Format: Book
• Published: Karger Publishers, 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Hyperuricemia is an independent risk factor for diabetic kidney disease (DKD) progression. Previous animal and cohort studies have reported that allopurinol administration could be of therapeutic benefit in diabetic subjects. However, there has been controversy regarding the effects of a...