Analysis of HIF-1α expression and genetic polymorphisms in human clear cell renal cell carcinoma

• Main Authors: Daniela Vargova (Author), Zuzana Kolková (Author), Jan Dargaj (Author), Lukas Bris (Author), Jan Luptak (Author), Zuzana Dankova (Author), Sona Franova (Author), Jan Svihra (Author), Pavol Slávik (Author), Martina Sutovska (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Clear cell renal cell carcinoma (ccRCC) is mostly diagnosed incidentally and has relatively high recurrence rates. Alterations in VHL/HIF and mTOR pathways are commonly present in ccRCC. The present study attempted to identify potential diagnostic markers at the biochemical and molecul...