Analysis of HIF-1α expression and genetic polymorphisms in human clear cell renal cell carcinoma

• Principais autores: Daniela Vargova (Autor), Zuzana Kolková (Autor), Jan Dargaj (Autor), Lukas Bris (Autor), Jan Luptak (Autor), Zuzana Dankova (Autor), Sona Franova (Autor), Jan Svihra (Autor), Pavol Slávik (Autor), Martina Sutovska (Autor)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2024-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Introduction: Clear cell renal cell carcinoma (ccRCC) is mostly diagnosed incidentally and has relatively high recurrence rates. Alterations in VHL/HIF and mTOR pathways are commonly present in ccRCC. The present study attempted to identify potential diagnostic markers at the biochemical and molecul...