The epigenetic role of HTR1A antagonist in facilitating GnRH expression for pubertal initiation control

Serotonin (5-hydroxytryptamine [5-HT]), a metabolite of tryptophan, acts on the components of the hypothalamus-hypophysis-gonad axis and induces puberty delay in mammals via 5-HT receptor 1A (HTR1A). However, the roles of HTR1A in the hypothalamus in pubertal regulation of gene expression are not fu...

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Main Authors: Shasha Zhou (Author), Yihang Shen (Author), Shaolian Zang (Author), Xiaoqin Yin (Author), Pin Li (Author)
Format: Book
Published: Elsevier, 2021-09-01T00:00:00Z.
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