TAAR1 agonists improve glycemic control, reduce body weight and modulate neurocircuits governing energy balance and feeding

• Main Authors: Nina Dedic (Author), Lien Wang (Author), Eva Hajos-Korcsok (Author), Jacob Hecksher-Sørensen (Author), Urmas Roostalu (Author), Steven P. Vickers (Author), Serena Wu (Author), Christoph Anacker (Author), Colleen Synan (Author), Philip G. Jones (Author), Snezana Milanovic (Author), Seth C. Hopkins (Author), Linda J. Bristow (Author), Kenneth S. Koblan (Author)
• Format: Book
• Published: Elsevier, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Metabolic Syndrome, which can be induced or exacerbated by current antipsychotic drugs (APDs), is highly prevalent in schizophrenia patients. Recent preclinical and clinical evidence suggest that agonists at trace amine-associated receptor 1 (TAAR1) have potential as a new treatment optio...