The Partial Duplication of the 5' Segment of KMT2A Revealed KMT2A-MLLT10 Rearrangement in a Boy with Acute Myeloid Leukemia

• Main Authors: Hiroko Fukushima (Author), Toru Nanmoku (Author), Sho Hosaka (Author), Yuni Yamaki (Author), Nobutaka Kiyokawa (Author), Takashi Fukushima (Author), Ryo Sumazaki (Author)
• Format: Book
• Published: Hindawi Limited, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The duplication of 5' segment of KMT2A is a rare molecular event in childhood leukemia, and the influence on prognosis is unknown. Here, we report on a boy who developed acute monocytic leukemia. Fluorescence in situ hybridization revealed the duplication of the 5' segment with 2 normal al...