Effects of a reactive oxygen species generator, napabucasin (BBI608), on tolerability, safety, pharmacokinetics, and QT/QTc interval in healthy volunteers
Abstract This study examined the safety, tolerability, and pharmacokinetics (PK) of napabucasin in healthy Asian and non‐Asian participants and investigated the potential for QT/QTc interval prolongation. This five‐part (A-E) study proceeded in a stepwise manner, unless stopping criteria were met. P...
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Main Authors: | Naoto Noda (Author), Takeshi Takagaki (Author), Yasuhide Yodo (Author), Yuzo Horibuchi (Author), Shuichi Iino (Author), Shunji Matsuki (Author), Yoichiro Ogama (Author), Hiroyoshi Kakuyama (Author) |
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Format: | Book |
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Wiley,
2021-10-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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