Inhibition of Indoxyl Sulfate-Induced Reactive Oxygen Species-Related Ferroptosis Alleviates Renal Cell Injury In Vitro and Chronic Kidney Disease Progression In Vivo

The accumulation of the uremic toxin indoxyl sulfate (IS) is a key pathological feature of chronic kidney disease (CKD). The effect of IS on ferroptosis and the role of IS-related ferroptosis in CKD are not well understood. We used a renal tubular cell model and an adenine-induced CKD mouse model to...

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Main Authors: Li-Ting Tsai (Author), Te-I Weng (Author), Ting-Yu Chang (Author), Kuo-Cheng Lan (Author), Chih-Kang Chiang (Author), Shing-Hwa Liu (Author)
Format: Book
Published: MDPI AG, 2023-10-01T00:00:00Z.
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