ATG5 is instrumental in the transition from autophagy to apoptosis during the degeneration of tick salivary glands.

• Main Authors: Yanan Wang (Author), Houshuang Zhang (Author), Li Luo (Author), Yongzhi Zhou (Author), Jie Cao (Author), Xuenan Xuan (Author), Hiroshi Suzuki (Author), Jinlin Zhou (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Female tick salivary glands undergo rapid degeneration several days post engorgement. This degeneration may be caused by the increased concentration of ecdysone in the hemolymph during the fast feeding period and both autophagy and apoptosis occur. In this work, we first proved autophagy-related gen...