Suppressing FXR promotes antiviral effects of bile acids via enhancing the interferon transcription

• Main Authors: Xue Liang (Author), Kunpeng Liu (Author), Xin Jia (Author), Cuiqin Cheng (Author), Meiqi Zhang (Author), Lingdong Kong (Author), Qiqi Li (Author), Zhe Liu (Author), Min Li (Author), Junliang Li (Author), Yao Wang (Author), Anlong Xu (Author)
• Format: Book
• Published: Elsevier, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Bile acids (BAs) are natural metabolites in mammals and have the potential to function as drugs against viral infection. However, the limited understanding of chenodeoxycholic acid (CDCA) receptors and downstream signaling, along with its lower suppression efficiency in inhibiting virus infection li...