Sox2 promotes expression of the ST6Gal-I glycosyltransferase in ovarian cancer cells

Abstract Background The ST6Gal-I glycosyltransferase, which adds α2-6-linked sialic acids to N-glycosylated proteins is upregulated in a wide range of malignancies including ovarian cancer. Prior studies have shown that ST6Gal-I-mediated sialylation of select surface receptors remodels intracellular...

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Autors principals: Kaitlyn A. Dorsett (Autor), Robert B. Jones (Autor), Katherine E. Ankenbauer (Autor), Anita B. Hjelmeland (Autor), Susan L. Bellis (Autor)
Format: Llibre
Publicat: BMC, 2019-10-01T00:00:00Z.
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