Exposure of LS-180 Cells to Drugs of Diverse Physicochemical and Therapeutic Properties Up-regulates P-glycoprotein Expression and Activity

Purpose. Drug transporters are increasingly recognized as important determinants of variability in drug disposition and therapeutic response, both in pre-clinical and clinical stages of drug development process. The role P-glycoprotein (P-gp) plays in drug interactions via its inhibition is well est...

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Main Authors: Alaa H Abuznait (Author), Shawn G Patrick (Author), Amal Kaddoumi (Author)
Format: Book
Published: Frontiers Media S.A., 2011-06-01T00:00:00Z.
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3rd Floor Main Library

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