In-Depth Characterization of EpiIntestinal Microtissue as a Model for Intestinal Drug Absorption and Metabolism in Human

The Caco-2 model is a well-accepted in vitro model for the estimation of fraction absorbed in human intestine. Due to the lack of cytochrome P450 3A4 (CYP3A4) activities, Caco-2 model is not suitable for the investigation of intestinal first-pass metabolism. The purpose of this study is to evaluate...

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Main Authors: Yunhai Cui (Author), Stephanie Claus (Author), David Schnell (Author), Frank Runge (Author), Caroline MacLean (Author)
Format: Book
Published: MDPI AG, 2020-04-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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