Differential microRNA Profiles and Their Functional Implications in Different Immunogenetic Subsets of Chronic Lymphocytic Leukemia

• Main Authors: Nikos Papakonstantinou (Author), Stavroula Ntoufa (Author), Elisavet Chartomatsidou (Author), Giorgio Papadopoulos (Author), Artemis Hatzigeorgiou (Author), Achiles Anagnostopoulos (Author), Katerina Chlichlia (Author), Paolo Ghia (Author), Marta Muzio (Author), Chrysoula Belessi (Author), Kostas Stamatopoulos (Author)
• Format: Book
• Published: BMC, 2013-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Critical processes of B-cell physiology, including immune signaling through the B-cell receptor (BcR) and/or Toll-like receptors (TLRs), are targeted by microRNAs. With this in mind and also given the important role of BcR and TLR signaling and microRNAs in chronic lymphocytic leukemia (CLL...