Quaternary Ammonium Palmitoyl Glycol Chitosan (GCPQ) Loaded with Platinum-Based Anticancer Agents-A Novel Polymer Formulation for Anticancer Therapy

• Автори: Yvonne Lerchbammer-Kreith (Автор), Michaela Hejl (Автор), Nadine S. Sommerfeld (Автор), Xian Weng-Jiang (Автор), Uchechukwu Odunze (Автор), Ryan D. Mellor (Автор), David G. Workman (Автор), Michael A. Jakupec (Автор), Andreas G. Schätzlein (Автор), Ijeoma F. Uchegbu (Автор), Mathea S. Galanski (Автор), Bernhard K. Keppler (Автор)
• Формат: Книга
• Опубліковано: MDPI AG, 2023-07-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Quaternary ammonium palmitoyl glycol chitosan (GCPQ) has already shown beneficial drug delivery properties and has been studied as a carrier for anticancer agents. Consequently, we synthesised cytotoxic platinum(IV) conjugates of cisplatin, carboplatin and oxaliplatin by coupling via amide bonds to...