Metformin Alleviates Steatohepatitis in Diet-Induced Obese Mice in a SIRT1-Dependent Way

• 主要な著者: Wan-rong Guo (著者), Juan Liu (著者), Li-dan Cheng (著者), Zi-yu Liu (著者), Xiao-bin Zheng (著者), Hua Liang (著者), Fen Xu (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2021-08-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Metformin is the first-line anti-diabetic drug for type 2 diabetes. It has been found to significantly reduce liver aminotransferase in nonalcoholic fatty liver disease (NAFLD). However, whether metformin improves NAFLD progression remains controversial. Sirtuin 1 (SIRT1), an NAD+-dependent deacetyl...