Aedes mosquito saliva modulates Rift Valley fever virus pathogenicity.

• Main Authors: Alain Le Coupanec (Author), Divya Babin (Author), Laurence Fiette (Author), Grégory Jouvion (Author), Patrick Ave (Author), Dorothee Misse (Author), Michèle Bouloy (Author), Valerie Choumet (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: Rift Valley fever (RVF) is a severe mosquito-borne disease affecting humans and domestic ruminants. Mosquito saliva contains compounds that counteract the hemostatic, inflammatory, and immune responses of the host. Modulation of these defensive responses may facilitate virus infection. I...