Hypoxia-ameliorated photothermal manganese dioxide nanoplatform for reversing doxorubicin resistance

• Main Authors: Zhenzhen Chen (Author), Zhihong Liu (Author), Qian Zhang (Author), Sheng Huang (Author), Zaizhong Zhang (Author), Xianquan Feng (Author), Lingjun Zeng (Author), Ding Lin (Author), Lie Wang (Author), Hongtao Song (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Drug resistance is a huge hurdle in tumor therapy. Tumor hypoxia contributes to chemotherapy resistance by inducing the hypoxia-inducible factor-1α (HIF-1α) pathway. To reduce tumor hypoxia, novel approaches have been devised, providing significant importance to reverse therapeutic resistance and im...