Single cell immune profiling of dengue virus patients reveals intact immune responses to Zika virus with enrichment of innate immune signatures.

• Main Authors: Yujiao Zhao (Author), Matthew Amodio (Author), Brent Vander Wyk (Author), Bram Gerritsen (Author), Mahesh M Kumar (Author), David van Dijk (Author), Kevin Moon (Author), Xiaomei Wang (Author), Anna Malawista (Author), Monique M Richards (Author), Megan E Cahill (Author), Anita Desai (Author), Jayasree Sivadasan (Author), Manjunatha M Venkataswamy (Author), Vasanthapuram Ravi (Author), Erol Fikrig (Author), Priti Kumar (Author), Steven H Kleinstein (Author), Smita Krishnaswamy (Author), Ruth R Montgomery (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The genus Flavivirus contains many mosquito-borne human pathogens of global epidemiological importance such as dengue virus, West Nile virus, and Zika virus, which has recently emerged at epidemic levels. Infections with these viruses result in divergent clinical outcomes ranging from asymptomatic t...