Dynamic Colon Model (DCM): A Cine-MRI Informed Biorelevant In Vitro Model of the Human Proximal Large Intestine Characterized by Positron Imaging Techniques

• Main Authors: Konstantinos Stamatopoulos (Author), Sharad Karandikar (Author), Mark Goldstein (Author), Connor O'Farrell (Author), Luca Marciani (Author), Sarah Sulaiman (Author), Caroline L. Hoad (Author), Mark J. H. Simmons (Author), Hannah K. Batchelor (Author)
• Format: Book
• Published: MDPI AG, 2020-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This work used in vivo MRI images of human colon wall motion to inform a biorelevant Dynamic Colon Model (DCM) to understand the interplay of wall motion, volume, viscosity, fluid, and particle motion within the colon lumen. Hydrodynamics and particle motion within the DCM were characterized using P...