Piracetam as a Therapeutic Agent for Doxorubicin-Induced Cognitive Deficits by Enhancing Cholinergic Functions and Reducing Neuronal Inflammation, Apoptosis, and Oxidative Stress in Rats

Cancer chemotherapy is known to cause cognitive defects in patients. Our study investigated the effect of piracetam (PIRA; 200 or 400 mg/kg) against doxorubicin (DOX)-induced cognitive deficits in a rat model. The cognitive parameters were analyzed using elevated plus-maze, novel object recognition,...

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Main Authors: Vasudevan Mani (Author), Syed Imam Rabbani (Author), Ali Shariq (Author), Palanisamy Amirthalingam (Author), Minhajul Arfeen (Author)
Format: Book
Published: MDPI AG, 2022-12-01T00:00:00Z.
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3rd Floor Main Library

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