Impact of process stress on protein stability in highly-loaded solid protein/PEG formulations from small-scale melt extrusion

As protein-based therapeutics often exhibit a limited stability in liquid formulations, there is a growing interest in the development of solid protein formulations due to improved protein stability in the solid state. We used small-scale (<3 g) ram and twin-screw extrusion for the solid stabiliz...

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Main Authors: Katharina Dauer (Author), Christian Werner (Author), Dirk Lindenblatt (Author), Karl Gerhard Wagner (Author)
Format: Book
Published: Elsevier, 2023-12-01T00:00:00Z.
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3rd Floor Main Library

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