Berberine Ameliorates High Glucose-Induced Cardiomyocyte Injury via AMPK Signaling Activation to Stimulate Mitochondrial Biogenesis and Restore Autophagic Flux

• প্রধান লেখক: Weijian Hang (লেখক), Benhong He (লেখক), Jiehui Chen (লেখক), Liangtao Xia (লেখক), Bing Wen (লেখক), Tao Liang (লেখক), Xu Wang (লেখক), Qianying Zhang (লেখক), Yue Wu (লেখক), Qingjie Chen (লেখক), Juan Chen (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Frontiers Media S.A., 2018-10-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Background: Type II diabetes (T2D)-induced cardiomyocyte hypertrophy is closely linked to the impairment of mitochondrial function. Berberine has been shown to be a promising effect for hypoglycemia in T2D models. High glucose-induced cardiomyocyte hypertrophy in vitro has been reported. The present...