The minor allele of the CREBRF rs373863828 p.R457Q coding variant is associated with reduced levels of myostatin in males: Implications for body composition

• Príomhchruthaitheoirí: Kate Lee (Údar), Sanaz Vakili (Údar), Hannah J. Burden (Údar), Shannon Adams (Údar), Greg C. Smith (Údar), Braydon Kulatea (Údar), Morag Wright-McNaughton (Údar), Danielle Sword (Údar), Conor Watene-O'Sullivan (Údar), Robert D. Atiola (Údar), Ryan G. Paul (Údar), Lindsay D. Plank (Údar), Prasanna Kallingappa (Údar), Frances King (Údar), Phillip Wilcox (Údar), Tony R. Merriman (Údar), Jeremy D. Krebs (Údar), Rosemary M. Hall (Údar), Rinki Murphy (Údar), Troy L. Merry (Údar), Peter R. Shepherd (Údar)
• Formáid: LEABHAR
• Foilsithe / Cruthaithe: Elsevier, 2022-05-01T00:00:00Z.
• Ábhair: article
• Rochtain ar líne: Connect to this object online.

Objective: The minor allele (A) of the rs373863828 variant (p.Arg457Gln) in CREBRF is restricted to indigenous peoples of the Pacific islands (including New Zealand Māori and peoples of Polynesia), with a frequency of up to 25% in these populations. This allele associates with a large increase in b...