Effect of Cyclodextrin Types and Co-Solvent on Solubility of a Poorly Water Soluble Drug

• Egile Nagusiak: Suporn Charumanee (Egilea), Siriporn Okonogi (Egilea), Jakkapan Sirithunyalug (Egilea), Peter Wolschann (Egilea), Helmut Viernstein (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2016-10-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

The aim of the study was to investigate the solubility of piroxicam (Prx) depending on the inclusion complexation with various cyclodextrins (CDs) and on ethanol as a co-solvent. The phase-solubility method was applied to determine drug solubility in binary and ternary systems. The results showed th...