EB virus-positive tumors are inhibited by rBCG expressing hGM-CSF and LMP2A

• Main Authors: Yingchun Yan (Author), Qing-Jie Xue (Author), Ang Liu (Author), Hui Wang (Author), Honghua Zhang (Author), Shuang Wang (Author), Longyu Zhao (Author), Yunqing Li (Author), Xiuzhen Li (Author), Yuanyuan Yang (Author), Ting Chen (Author), Shigen Li (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

For the development of safe and effective EBV (Epstein-Barr virus) vaccines, the Ag85A signal peptide from M. tuberculosis H37Rv was used to construct a recombinant secretory BCG (Bacillus Chalmette-Guérin) plasmid. The Ag85A gene, fused to the EBV LMP2A (latent membrane protein) and hGM-CSF (human...