Acid-Sensing Ion Channels as Potential Therapeutic Targets in Neurodegeneration and Neuroinflammation
Acid-sensing ion channels (ASICs) are a family of proton-sensing channels that are voltage insensitive, cation selective (mostly permeable to Na+), and nonspecifically blocked by amiloride. Derived from 5 genes (ACCN1-5), 7 subunits have been identified, 1a, 1b, 2a, 2b, 3, 4, and 5, that are widely...
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| Main Authors: | , , |
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| Format: | Book |
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Hindawi Limited,
2017-01-01T00:00:00Z.
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| Call Number: |
A1234.567 |
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| Copy 1 | Available |