Effect of polymorphisms in drug metabolism and transportation on plasma concentration of atorvastatin and its metabolites in patients with chronic kidney disease

• मुख्य लेखकों: Zebin Jiang (लेखक), Zemin Wu (लेखक), Ruixue Liu (लेखक), Qin Du (लेखक), Xian Fu (लेखक), Min Li (लेखक), Yongjun Kuang (लेखक), Shen Lin (लेखक), Jiaxuan Wu (लेखक), Weiji Xie (लेखक), Ganggang Shi (लेखक), Yanqiang Peng (लेखक), Fuchun Zheng (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2023-02-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Dyslipidemia due to renal insufficiency is a common complication in patients with chronic kidney diseases (CKD), and a major risk factor for the development of cardiovascular events. Atorvastatin (AT) is mainly used in the treatment of dyslipidemia in patients with CKD. However, response to the ator...