Simultaneous Imaging and Therapy Using Epitope-Specific Anti-Epidermal Growth Factor Receptor (EGFR) Antibody Conjugates

• मुख्य लेखकों: Anjong Florence Tikum (लेखक), Anand Krishnan Nambisan (लेखक), Jessica Pougoue Ketchemen (लेखक), Hanan Babeker (लेखक), Musharraf N. Khan (लेखक), Emina E. Torlakovic (लेखक), Humphrey Fonge (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2022-09-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Matuzumab and nimotuzumab are anti-EGFR monoclonal antibodies that bind to different epitopes of domain III of EGFR. We developed ⁸⁹Zr-matuzumab as a PET probe for diagnosis/monitoring of response to treatment of a noncompeting anti-EGFR nimotuzumab antibody drug conjugate (AD...