Simultaneous Imaging and Therapy Using Epitope-Specific Anti-Epidermal Growth Factor Receptor (EGFR) Antibody Conjugates

Simultaneous Imaging and Therapy Using Epitope-Specific Anti-Epidermal Growth Factor Receptor (EGFR) Antibody Conjugates

Matuzumab and nimotuzumab are anti-EGFR monoclonal antibodies that bind to different epitopes of domain III of EGFR. We developed <sup>89</sup>Zr-matuzumab as a PET probe for diagnosis/monitoring of response to treatment of a noncompeting anti-EGFR nimotuzumab antibody drug conjugate (AD...

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Main Authors: Anjong Florence Tikum (Author), Anand Krishnan Nambisan (Author), Jessica Pougoue Ketchemen (Author), Hanan Babeker (Author), Musharraf N. Khan (Author), Emina E. Torlakovic (Author), Humphrey Fonge (Author)
Format: Book
Published: MDPI AG, 2022-09-01T00:00:00Z.
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3rd Floor Main Library

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