Simultaneous Imaging and Therapy Using Epitope-Specific Anti-Epidermal Growth Factor Receptor (EGFR) Antibody Conjugates

• 主要な著者: Anjong Florence Tikum (著者), Anand Krishnan Nambisan (著者), Jessica Pougoue Ketchemen (著者), Hanan Babeker (著者), Musharraf N. Khan (著者), Emina E. Torlakovic (著者), Humphrey Fonge (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2022-09-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Matuzumab and nimotuzumab are anti-EGFR monoclonal antibodies that bind to different epitopes of domain III of EGFR. We developed ⁸⁹Zr-matuzumab as a PET probe for diagnosis/monitoring of response to treatment of a noncompeting anti-EGFR nimotuzumab antibody drug conjugate (AD...