Simultaneous Imaging and Therapy Using Epitope-Specific Anti-Epidermal Growth Factor Receptor (EGFR) Antibody Conjugates

• Hoofdauteurs: Anjong Florence Tikum (Auteur), Anand Krishnan Nambisan (Auteur), Jessica Pougoue Ketchemen (Auteur), Hanan Babeker (Auteur), Musharraf N. Khan (Auteur), Emina E. Torlakovic (Auteur), Humphrey Fonge (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2022-09-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Matuzumab and nimotuzumab are anti-EGFR monoclonal antibodies that bind to different epitopes of domain III of EGFR. We developed ⁸⁹Zr-matuzumab as a PET probe for diagnosis/monitoring of response to treatment of a noncompeting anti-EGFR nimotuzumab antibody drug conjugate (AD...