Combination of DNA Vaccine and Immune Checkpoint Blockades Improves the Immune Response in an Orthotopic Unresectable Glioblastoma Model

Combination of DNA Vaccine and Immune Checkpoint Blockades Improves the Immune Response in an Orthotopic Unresectable Glioblastoma Model

Combination immunotherapy has emerged as a promising strategy to increase the immune response in glioblastoma (GBM) and overcome the complex immunosuppression occurring in its microenvironment. In this study, we hypothesized that combining DNA vaccines-to stimulate a specific immune response-and dua...

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Main Authors: Mathilde Bausart (Author), Kevin Vanvarenberg (Author), Bernard Ucakar (Author), Alessandra Lopes (Author), Gaëlle Vandermeulen (Author), Alessio Malfanti (Author), Véronique Préat (Author)
Format: Book
Published: MDPI AG, 2022-05-01T00:00:00Z.
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3rd Floor Main Library

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