Maternal obesity causes fetal hypothalamic insulin resistance and disrupts development of hypothalamic feeding pathways

• Main Authors: L. Dearden (Author), S. Buller (Author), I.C. Furigo (Author), D.S. Fernandez-Twinn (Author), S.E. Ozanne (Author)
• Formato: Livro
• Publicado em: Elsevier, 2020-12-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Objective: Perinatal exposure to maternal obesity results in predisposition of offspring to develop obesity later in life. Increased weight gain in offspring exposed to maternal obesity is usually associated with hyperphagia, implicating altered central regulation of food intake as a cause. We aimed...