Multitarget ligands that comprise opioid/nonopioid pharmacophores for pain management: Current state of the science
Chronic pain, which affects more than one-third of the world's population, represents one of the greatest medical challenges of the 21st century, yet its effective management remains sub-optimal. The 'gold standard' for the treatment of moderate to severe pain consists of opioid ligan...
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Elsevier,
2024-11-01T00:00:00Z.
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