Quality control of cell-based high-throughput drug screening

• Egile Nagusiak: Zhiyun Zhang (Egilea), Ni Guan (Egilea), Ting Li (Egilea), Dale E. Mais (Egilea), Mingwei Wang (Egilea)
• Formatua: Liburua
• Argitaratua: Elsevier, 2012-10-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

The pharmaceutical industry is presently suffering difficult times due to low productivity of new molecular entities. As a major source of drug leads, high-throughput screening (HTS) has been often criticized for its 'dead end' lead compounds. However, the fruitful achievements resulting f...