Quality control of cell-based high-throughput drug screening

• Main Authors: Zhiyun Zhang (Author), Ni Guan (Author), Ting Li (Author), Dale E. Mais (Author), Mingwei Wang (Author)
• Formato: Livro
• Publicado em: Elsevier, 2012-10-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

The pharmaceutical industry is presently suffering difficult times due to low productivity of new molecular entities. As a major source of drug leads, high-throughput screening (HTS) has been often criticized for its 'dead end' lead compounds. However, the fruitful achievements resulting f...