Cellular and Humoral Immune Responses and Breakthrough Infections After Two Doses of BNT162b Vaccine in Healthcare Workers (HW) 180 Days After the Second Vaccine Dose

• Main Authors: Alessandra Mangia (Author), Nicola Serra (Author), Giovanna Cocomazzi (Author), Vincenzo Giambra (Author), Stefano Antinucci (Author), Alberto Maiorana (Author), Francesco Giuliani (Author), Emanuele Montomoli (Author), Paolo Cantaloni (Author), Alessandro Manenti (Author), Valeria Piazzolla (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BackgroundImmunity and clinical protection induced by mRNA vaccines against SARS-CoV-2 have been shown to decline overtime. To gather information on the immunity profile deemed sufficient in protecting against hospitalization, we tested IgG levels, interferon-gamma (IFN-γ) secretion, and neutralizin...