Calcium Dobesilate Restores Autophagy by Inhibiting the VEGF/PI3K/AKT/mTOR Signaling Pathway

• Main Authors: Yue Wang (Author), Yun-hong Lu (Author), Chao Tang (Author), Mei Xue (Author), Xiao-yu Li (Author), Yun-peng Chang (Author), Ying Cheng (Author), Ting Li (Author), Xiao-chen Yu (Author), Bei Sun (Author), Chun-jun Li (Author), Li-ming Chen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Calcium dobesilate (CaD), an effective drug for the treatment of diabetic microvascular complications, especially diabetic retinopathy, is widely used in the clinic. Interestingly, several studies have indicated that CaD is therapeutic for diabetic kidney disease (DKD). Recently, evidence...