Comprehensive landscape of epigenetic-dysregulated lncRNAs reveals a profound role of enhancers in carcinogenesis in BC subtypes

• Автори: Hongying Zhao (Автор), Xiaoqin Liu (Автор), Lei Yu (Автор), Shihua Lin (Автор), Caiyu Zhang (Автор), Haotian Xu (Автор), Zhijun Leng (Автор), Waidong Huang (Автор), Junjie Lei (Автор), Tengyue Li (Автор), Jing Li (Автор), Fan Yang (Автор), Li Wang (Автор)
• Формат: Книга
• Опубліковано: Elsevier, 2021-03-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Aberrant expression of long non-coding RNAs (lncRNA) is associated with altered DNA methylation and histone modifications during carcinogenesis. However, identifying epigenetically dysregulated lncRNAs and characterizing their functional mechanisms in different cancer subtypes are still major challe...