Comprehensive landscape of epigenetic-dysregulated lncRNAs reveals a profound role of enhancers in carcinogenesis in BC subtypes

• Main Authors: Hongying Zhao (Author), Xiaoqin Liu (Author), Lei Yu (Author), Shihua Lin (Author), Caiyu Zhang (Author), Haotian Xu (Author), Zhijun Leng (Author), Waidong Huang (Author), Junjie Lei (Author), Tengyue Li (Author), Jing Li (Author), Fan Yang (Author), Li Wang (Author)
• Format: Book
• Published: Elsevier, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aberrant expression of long non-coding RNAs (lncRNA) is associated with altered DNA methylation and histone modifications during carcinogenesis. However, identifying epigenetically dysregulated lncRNAs and characterizing their functional mechanisms in different cancer subtypes are still major challe...