Genetic Polymorphisms Associated with Cyclophosphamide Outcome and Risk of Toxicity in Patients with Lupus Nephritis

• Main Authors: Yen Yen Ari Indrawijaya (Author), Laniyati Hamijoyo (Author), Aluicia Anita Artarini (Author), Maria Immaculata Iwo (Author)
• Formato: Livro
• Publicado em: Interna Publishing, 2023-07-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

A 6-month cyclophosphamide induction therapy followed by maintenance therapy every three months is the first-line treatment for Class III, IV, and V lupus nephritis. Among the 139 single nucleotide polymorphisms (SNPs) associated with cyclophosphamide, four SNPs, namely rs4244285, rs4802101, rs72545...