Design, synthesis, and biological evaluation of arylmethylpiperidines as Kv1.5 potassium channel inhibitors
Kv1.5 potassium channel, encoded by KCNA5, is a promising target for the treatment of atrial fibrillation, one of the common arrhythmia. A new series of arylmethylpiperidines derivatives based on DDO-02001 were synthesised and evaluated for their ability to inhibit Kv1.5 channel. Among them, compoun...
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| Główni autorzy: | , , , , |
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| Format: | Książka |
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Taylor & Francis Group,
2022-12-01T00:00:00Z.
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A1234.567 |
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