Oleanolic acid exerts bone protective effects in ovariectomized mice by inhibiting osteoclastogenesis

• Main Authors: Dongfeng Zhao (Author), Xiaofeng Li (Author), Yongjian Zhao (Author), Ping Qiao (Author), Dezhi Tang (Author), Yan Chen (Author), Chunchun Xue (Author), Chenguang Li (Author), Shufen Liu (Author), Jing Wang (Author), Sheng Lu (Author), Qi Shi (Author), Yan Zhang (Author), Yufeng Dong (Author), Yongjun Wang (Author), Bing Shu (Author), Xu Feng (Author)
• Format: Book
• Published: Elsevier, 2018-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Postmenopausal osteoporosis (POP) is quite prevalent and many new drugs are under development to obtain better therapeutic outcomes. Oleanolic acid (OA) has been reported to prevent bone loss in ovariectomized (OVX) rats by stimulating osteoblastogenesis. One previous study has demonstrated that ace...