Engineered platelets-based drug delivery platform for targeted thrombolysis

• Main Authors: Songli Wang (Author), Ruifeng Wang (Author), Nana Meng (Author), Linwei Lu (Author), Jun Wang (Author), Jianfen Zhou (Author), Jiasheng Lu (Author), Qianzhu Xu (Author), Cao Xie (Author), Changyou Zhan (Author), Yao Li (Author), Yang Yu (Author), Weiyue Lu (Author), Min Liu (Author)
• Format: Book
• Published: Elsevier, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Thrombolytic agents have thus far yielded limited therapeutic benefits in the treatment of thrombotic disease due to their short half-life, low targeting ability, and association with serious adverse reactions, such as bleeding complications. Inspired by the natural roles of platelets during thrombu...