Bioequivalence clinical trial simulation: a case study of apalutamide administered in applesauce versus whole tablets
Abstract Patients who have difficulty swallowing apalutamide tablets may benefit from administration in a food vehicle that is easier to swallow. In a previous single-dose study conducted in healthy male volunteers (n = 12) a larger peak exposure was observed (+ 27.6%) for apalutamide in applesauce...
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SpringerOpen,
2023-08-01T00:00:00Z.
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