Bioequivalence clinical trial simulation: a case study of apalutamide administered in applesauce versus whole tablets

Abstract Patients who have difficulty swallowing apalutamide tablets may benefit from administration in a food vehicle that is easier to swallow. In a previous single-dose study conducted in healthy male volunteers (n = 12) a larger peak exposure was observed (+ 27.6%) for apalutamide in applesauce...

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Main Authors: Alex Yu (Author), Oliver Ackaert (Author)
Format: Book
Published: SpringerOpen, 2023-08-01T00:00:00Z.
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3rd Floor Main Library

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