Host factors and early treatments to restrict paediatric HIV infection and early disease progression

• Main Authors: Ketty Gianesin (Author), Raffaella Petrara (Author), Riccardo Freguja (Author), Marisa Zanchetta (Author), C.arlo Giaquinto (Author), Anita De Rossi (Author)
• Format: Book
• Published: Elsevier, 2015-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A body of evidence indicates that a threshold level of the virus is required to establish systemic and persistent HIV infection in the host and that this level depends on virus-host interactions. Mother-to-child transmission (MTCT) of HIV is the main source of paediatric HIV infection and occurs whe...