Oral Administration of Efavirenz Dysregulates the <i>Tph2</i> Gene in Brain Serotonergic Areas and Alters Weight and Mood in Mice

Oral Administration of Efavirenz Dysregulates the <i>Tph2</i> Gene in Brain Serotonergic Areas and Alters Weight and Mood in Mice

Most HIV-antiretroviral drugs have adverse effects. Efavirenz (EFV) is an example of a drug with neuropsychiatric effects, such as anxiety, depression, and suicidal thoughts, in people living with HIV (PLWH). The mechanisms by which EFV causes neuropsychiatric alterations in PLWH are complex, multif...

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Main Authors: Sandra Angélica Rojas-Osornio (Author), Minerva Crespo-Ramírez (Author), Vladimir Paredes-Cervantes (Author), Antonio Mata-Marín (Author), Ricardo Martínez-Lara (Author), Miguel Pérez de la Mora (Author), Emiliano Tesoro-Cruz (Author)
Format: Book
Published: MDPI AG, 2024-06-01T00:00:00Z.
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