Oral Administration of Efavirenz Dysregulates the <i>Tph2</i> Gene in Brain Serotonergic Areas and Alters Weight and Mood in Mice

• Үндсэн зохиолчид: Sandra Angélica Rojas-Osornio (Зохиогч), Minerva Crespo-Ramírez (Зохиогч), Vladimir Paredes-Cervantes (Зохиогч), Antonio Mata-Marín (Зохиогч), Ricardo Martínez-Lara (Зохиогч), Miguel Pérez de la Mora (Зохиогч), Emiliano Tesoro-Cruz (Зохиогч)
• Формат: Ном
• Хэвлэсэн: MDPI AG, 2024-06-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Most HIV-antiretroviral drugs have adverse effects. Efavirenz (EFV) is an example of a drug with neuropsychiatric effects, such as anxiety, depression, and suicidal thoughts, in people living with HIV (PLWH). The mechanisms by which EFV causes neuropsychiatric alterations in PLWH are complex, multif...