Oral Administration of Efavirenz Dysregulates the <i>Tph2</i> Gene in Brain Serotonergic Areas and Alters Weight and Mood in Mice

• Hlavní autoři: Sandra Angélica Rojas-Osornio (Autor), Minerva Crespo-Ramírez (Autor), Vladimir Paredes-Cervantes (Autor), Antonio Mata-Marín (Autor), Ricardo Martínez-Lara (Autor), Miguel Pérez de la Mora (Autor), Emiliano Tesoro-Cruz (Autor)
• Médium: Kniha
• Vydáno: MDPI AG, 2024-06-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Most HIV-antiretroviral drugs have adverse effects. Efavirenz (EFV) is an example of a drug with neuropsychiatric effects, such as anxiety, depression, and suicidal thoughts, in people living with HIV (PLWH). The mechanisms by which EFV causes neuropsychiatric alterations in PLWH are complex, multif...