Oral Administration of Efavirenz Dysregulates the <i>Tph2</i> Gene in Brain Serotonergic Areas and Alters Weight and Mood in Mice

• প্রধান লেখক: Sandra Angélica Rojas-Osornio (Author), Minerva Crespo-Ramírez (Author), Vladimir Paredes-Cervantes (Author), Antonio Mata-Marín (Author), Ricardo Martínez-Lara (Author), Miguel Pérez de la Mora (Author), Emiliano Tesoro-Cruz (Author)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: MDPI AG, 2024-06-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Most HIV-antiretroviral drugs have adverse effects. Efavirenz (EFV) is an example of a drug with neuropsychiatric effects, such as anxiety, depression, and suicidal thoughts, in people living with HIV (PLWH). The mechanisms by which EFV causes neuropsychiatric alterations in PLWH are complex, multif...