Mice doubly deficient in Six4 and Six5 show ventral body wall defects reproducing human omphalocele

• Hoofdauteurs: Masanori Takahashi (Auteur), Masaru Tamura (Auteur), Shigeru Sato (Auteur), Kiyoshi Kawakami (Auteur)
• Formaat: Boek
• Gepubliceerd in: The Company of Biologists, 2018-10-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Omphalocele is a human congenital anomaly in ventral body wall closure and may be caused by impaired formation of the primary abdominal wall (PAW) and/or defects in abdominal muscle development. Here, we report that mice doubly deficient in homeobox genes Six4 and Six5 showed the same ventral body w...