Design, synthesis, and biological activity evaluation of dihydromyricetin derivatives against SARS-CoV-2-Omicron virus

• मुख्य लेखकों: Cong Wu (लेखक), Qi Jiang (लेखक), Hui Zhong (लेखक), Xudong Zhou (लेखक), Leping Liu (लेखक), Tong Pan (लेखक), Chao Liu (लेखक), Wei Wang (लेखक), Wenbing Sheng (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

An oxidising and substituting one-pot reaction strategy has been developed to synthesise dihydromyricetin derivatives with the aim of enhancing the inhibitory activity of dihydromyricetin against SARS-CoV-2. Different ω-methoxy-ω-oxeylkyl was introduced in C7-OH site and yielded eight analogs, all o...