Pharmacokinetics of a microdosed cocktail of three direct oral anticoagulants in children with congenital heart defects: study protocol for a single-centre clinical trial (DOAC-Child)

Introduction Direct oral anticoagulants (DOACs) are direct inhibitors of coagulation factor Xa and are frequently used in adults for different indications such as deep vein thrombosis or non-valvular atrial fibrillation. Paediatric patients might benefit as well from DOACs because the simplicity and...

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Main Authors: Matthias Gorenflo (Author), Victoria C. Ziesenitz (Author), Gerd Mikus (Author), Simon A Hermann (Author), Kristine Chobanyan-Jürgens (Author)
Format: Book
Published: BMJ Publishing Group, 2023-12-01T00:00:00Z.
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