Beyond bispecificity: Controlled Fab arm exchange for the generation of antibodies with multiple specificities
Controlled Fab arm exchange (cFAE) has proven to be a generic and versatile technology for the efficient generation of IgG-like bispecific antibodies (DuoBodies or DBs), with several in clinical development and one product, amivantamab, approved by the Food and Drug Administration. In this study, we...
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Main Authors: | Desislava Yanakieva (Author), Lukas Pekar (Author), Andreas Evers (Author), Markus Fleischer (Author), Stephan Keller (Author), Dirk Mueller-Pompalla (Author), Lars Toleikis (Author), Harald Kolmar (Author), Stefan Zielonka (Author), Simon Krah (Author) |
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Format: | Book |
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Taylor & Francis Group,
2022-12-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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